PFC Ludogorets was founded in 1945 in Razgrad and for more than six decades has been an integral part of Bulgarian football. In the early years of its existence, the club mainly participated in regional championships, and during the 1961/62 season, for the first time, reached the then "B" group. In the 1990s, the team competed under the name "Antibiotik" before restoring its historical identity as Ludogorets.

The true transformation of the club began in 2010. After extensive investments in the development of the team and infrastructure, Ludogorets quickly became one of the leading forces in Bulgarian football. Under the leadership of Ivaylo Petev, the team won the Eastern "B" group during the 2010/11 season and for the first time in its history qualified for the top tier.

Even in its debut season in the "A" group, Ludogorets achieved something unprecedented. In 2012, the "Eagles" won the championship title, the Bulgarian Cup, and the Supercup, becoming the first club outside Sofia to triumph with the title in their first season in the elite. This marked the beginning of the most successful period in the club's history and a new era in Bulgarian football.

In the following years, Ludogorets established itself as the absolute hegemon on the domestic scene. The club won 14 consecutive championship titles, secured 4 Bulgarian Cups and 9 Bulgarian Supercups, setting records unparalleled in Bulgarian football history.

Alongside domestic successes, Ludogorets also built an impressive European resume. As early as 2013, the club reached the Europa League round of 16 after eliminating Lazio – the first such success for a Bulgarian team in decades.

During the 2014/15 season, Ludogorets qualified for the group stage of the Champions League for the first time following a dramatic victory over Steaua. In the tournament, the "Eagles" faced European giants such as Real Madrid, Liverpool, and Basel, recording a historic first win for a Bulgarian club in the Champions League group stage – 1:0 against Basel in Sofia.

The second historic campaign in Europe's most prestigious club tournament came in the 2016/17 season. Ludogorets passed the qualifiers and landed in a group with Arsenal, Paris Saint-Germain, and Basel. The Bulgarian champion completed the group stage without an away loss, earned points against PSG and Basel, and continued into the knockout phase of the Europa League.

In total, Ludogorets has two participations in the Champions League group stage, nine participations in the Europa League, and one in the Conference League, making them the most consistent Bulgarian participant in European club tournaments in the 21st century.

Over the years, the "Eagles" have faced some of the biggest clubs in world football. Among them are Real Madrid, Liverpool, Paris Saint-Germain, Arsenal, Inter, Milan, Lazio, Olympique Lyon, Athletic Bilbao, Ajax, Bayer Leverkusen, Roma, Tottenham, Fenerbahce, Viktoria Plzen, Braga, Hoffenheim, PSV Eindhoven, Basel, Dinamo Zagreb, Crvena Zvezda, and many other established European clubs.

Alongside sporting achievements, the club has consistently invested in developing its infrastructure. "Huvepharma Arena" has become one of the most modern football stadiums in Bulgaria, and the Ludogorets Academy develops young footballers who gradually make their way into the first team and the national squads.

Today, PFC Ludogorets is a symbol of professional management, development, and consistency. With its numerous trophies, record series of championship titles, and regular participation in European club tournaments, the club is established as the most successful Bulgarian football team of the 21st century and a worthy representative of Bulgaria on the international stage.